About

Developing the right medicines for the right time

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What if we knew precisely how to treat or reverse early-stage disease, so it never progresses to later, more severe stages?

At Etiome, we know that many diseases begin to affect physiological processes well before symptoms emerge, and that these processes evolve as disease progresses. We have discovered that windows of the disease continuum are hidden within individual patient tissue, and that when uncovered and integrated across populations, these windows can reveal the full trajectory of disease, including its initial causes and downstream effects.

By applying single-cell omics and artificial intelligence, we uncover subtle, hidden patterns of progression to identify disease-modifying targets at critical inflection points for therapeutic intervention.

We believe that:

  • Disease progression can be characterized by dynamic molecular and cellular representations with temporal resolution, enabling more precise target and biomarker discovery.
  • Medicines designed for specific biological stages of disease, not just late-stage disease, will outperform one-size-fits-all approaches and unlock preemptive intervention.
  • Biomarkers tied to underlying biology are dynamic across stages of disease and reveal responder populations for stage-specific therapeutics.
  • Engaging individuals at the right biological moment, even during silent stages of disease, will enable earlier intervention, measurable impact, and better outcomes.

Origins

The name Etiome (EH-tee-ohm) emerged from the fusion of two powerful scientific concepts: etiology, or the cause of a disease, and omics, or the large-scale exploration of biological systems.

The combination reflects the company’s mission to develop the tools, insights, and medicines needed to create a true preemptive healthcare system that prioritizes long-term health and well-being. Originating from Flagship Pioneering’s Preemptive Health and Medicine initiative, an effort aimed at pioneering a new field to protect, maintain, or improve people's health before they get sick, Etiome was founded in 2021 with a vision of a healthier future.

Team

Leadership

Adrian Rawcliffe

Chief Executive Officer
CEO-Partner, Flagship Pioneering

Scott Lipnick, Ph.D.

Co-Founder and President
Origination Partner, Flagship Pioneering

Jean Lachowicz, Ph.D., MBA

Chief Scientific Officer

Yann Echelard, Ph.D.

Chief Operating Officer
Operating Partner, Flagship Pioneering

Katharine von Herrmann, Ph.D.

Co-Founder & Chief Innovation Officer
Principal, Flagship Pioneering

Sandi Engle, PhD

VP, Head of Biology

Artem Sokolov, PhD

Sr. Director, Head of Computational Biology

Founding Team

Noubar Afeyan, Ph.D.

Co-Founder
Founder and CEO, Flagship Pioneering

Avak Kahvejian, Ph.D.

Founding CEO and Preferred Director
President of Flagship Labs and General Partner, Flagship Pioneering

Scott Lipnick, Ph.D.

Co-Founder and President
Origination Partner, Flagship Pioneering

Torben Straight Nissen, Ph.D.

Co-Founder and Chairman of the Board
Executive Partner, Flagship Pioneering

Yann Echelard, Ph.D.

Chief Operating Officer
Operating Partner, Flagship Pioneering

Katharine von Herrmann, Ph.D.

Co-Founder & Chief Innovation Officer
Principal, Flagship Pioneering

Board of Directors

Torben Straight Nissen, Ph.D.

Co-Founder and Chairman of the Board
Executive Partner, Flagship Pioneering

Avak Kahvejian, Ph.D.

Founding CEO and Preferred Director
President of Flagship Labs and General Partner, Flagship Pioneering

Raj Panjabi, M.D.

Director
Senior Partner, Flagship Pioneering

Gregory J. Moore, M.D., Ph.D.

Director
Senior Advisor, Gates Ventures

Careers

Are you passionate about applying novel science to change the health paradigm?

Learn more about our career opportunities
Careers